Old Mansions - Vacation Rentals in Historic Southwest

1 mi. from Mayo Clinic; Cozy, Clean From US $127
         

9.6 (97 Reviews)
House
  • Air Conditioner
  • Parking
  • TV
Covered By Faith Downtown- Blessing House From US $129
         

9.7 (5 Reviews)
House
  • Air Conditioner
  • Parking
  • Wheelchair Accessible
Home2 Suites by Hilton Rochester Mayo Clinic Area From US $131
         

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9.6 (877 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Magical Nest Hideaway From US $65
         

10.0 (134 Reviews)
House
  • Air Conditioner
  • Parking
  • TV
A Luxury Bungalow Near Mayo Clinic From US $192
         

10.0 (61 Reviews)
House
  • Air Conditioner
  • Parking
  • TV
☆Dee Dee's Den: A Dharma Dwellings Parent Company☆ From US $363
         

10.0 (45 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly

Luxury Places to Stay in Historic Southwest

Over 323+ Luxury Places to Stay in or Near Historic Southwest
RARE! Pool, hot tub, garden &chickens! 4m to Mayo From US $835
         

10.0 (1 Review)
House
  • Pool
  • Security/Safety
  • Barbecue/Outdoor Cooking
Villa LaRhea From US $785
         

9.6 (4 Reviews)
House
  • Air Conditioner
  • Parking
  • TV
Beautiful, Private, Nature & Hot tub! 4 miles to Mayo From US $655
         

10.0 (2 Reviews)
House
  • Air Conditioner
  • Security/Safety
  • Bedding/Linens
Luxury Stay/Theater/No step entry/Dogs Welcome From US $489
         

10.0 (19 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Luxurious 5-BR Retreat with Gym & Game Area From US $481
         

10.0 (30 Reviews)
House
  • Air Conditioner
  • Parking
  • TV

Top-Rated Vacation Rentals with a Pool in Historic Southwest

Over 71+ Top-Rated Vacation Rentals with a Pool in or Near Historic Southwest
Newly Remodeled Home 1 mile from Mayo Clinic From US $149
         

10.0 (8 Reviews)
House
  • Air Conditioner
  • Parking
  • Pool
Unit 2365J | 2bd/2bth | Single-Family Home From US $226
         

10.0 (2 Reviews)
House
  • Air Conditioner
  • Parking
  • Pool
The Berkman From US $216
         

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9.6 (368 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
Residence Inn by Marriott Rochester Mayo Clinic Area South From US $107
         

Spark by Hilton Rochester South From US $79
         

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9.4 (317 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool

Pet-Friendly Vacation Rentals in Historic Southwest

Over 113+ Pet-Friendly Vacation Rentals in or Near Historic Southwest
2 Bedroom Brand New Apartment Near Mayo, Park Free From US $180
         

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10.0 (5 Reviews)
Apartment
  • Air Conditioner
  • Pet Friendly
  • Accessibility
1742 Uptown/Stylish w/Updates, 3BD, Walk to Mayo, Pet Friendly From US $218
         

The Hygge House/A Cozy Guest House 15 min from Downtown From US $180
         

10.0 (19 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
☆Poppy's Paradise: A Dharma Dwellings Designed Home☆ From US $241
         

10.0 (14 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Meet Bev, a charming 2-bedroom, pet-friendly home in Rochester From US $198
         

1 mile to Mayo 2 step entry Brave Covered By Faith From US $223
         

10.0 (9 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly

Large Vacation Homes & Villas in Historic Southwest

Over 23+ Large Vacation Homes & Villas in or Near Historic Southwest
Luxury Home From US $199
         

New
Villa
  • Air Conditioner
  • Parking
  • Child Friendly
Entertainment for the whole family. Sleeps up to 10. From US $210
         

3 blks to St. Marys 3,800 sq ft CoveredByFaith From US $163
         

No Steps Close to Mayo & Shopping Covered By Faith From US $154
         

9.4 (44 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly

Wheelchair Accessible Vacation Homes in Historic Southwest

Over 77+ Wheelchair Accessible Vacation Homes in or Near Historic Southwest
House in the trees with City View From US $159
         

9.8 (25 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
Covered By Faith Downtown Rentals- Trust House From US $179
         

10.0 (1 Review)
House
  • Air Conditioner
  • Parking
  • Wheelchair Accessible
Hampton Inn & Suites Rochester-North From US $110
         

9.2 (1006 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool

Historic Southwest Varoom and Airbnb Places to Stay Under $200

Over 204+ Historic Southwest Varoom and Airbnb Places to Stay Under $200
Easter Eggs From US $77
         

10.0 (2 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Security/Safety
Candlewood Suites Rochester Mayo Clinic Area by IHG From US $112
         

Recliners. Single Level Living. Walk in shower. From US $168
         

Next to Mayo Clinic 518A From US $130
         

10.0 (22 Reviews)
House
  • Air Conditioner
  • Parking
  • TV
Beautifully Designed Space. 1 Mile to Mayo Clinic. From US $167
         

Quaint Home 2 miles from Mayo Handicap Accessible From US $122
         

Instantly Bookable Vacation Homes in Historic Southwest

Over 131+ Instantly Bookable Vacation Homes in or Near Historic Southwest
ADA Compliant Home 10 Min. From Mayo Clinic! From US $236
         

10.0 (16 Reviews)
House
  • Air Conditioner
  • Parking
  • TV
Lux 3 BR mins to Mayo & Dwtwn I Charming Haven From US $227
         

10.0 (6 Reviews)
House
  • Air Conditioner
  • Parking
  • Pet Friendly
The June/A one bedroom basement apartment, 3 mi to Mayo Clinic From US $127
         

10.0 (5 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
Hart House/One Bed, 1 Ba, St Mary's Mayo Clinic from the Front Porch From US $159
         

10.0 (4 Reviews)
House
  • Air Conditioner
  • Pet Friendly
  • Security/Safety

About Historic Southwest Vacation Rentals

With more than 332 Historic Southwest vacation rentals, we can help you find a place to stay. These rentals, including vacation rentals, Old Mansions and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at a rental property in Historic Southwest.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With Old Mansions Historic Southwest, you have the flexibility of comparing different options of various deals with a single click. Looking for a rental by owner with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner, and other popular Airbnb-style properties in Historic Southwest. Places to stay near Historic Southwest are 776.21 ft² on average, with prices averaging $179 a night.

Old Mansions makes it easy and safe to find and compare vacation rentals in Historic Southwest with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

Top Rental Accommodation Types in Historic Southwest

Type Count
Vacation Homes 200
Hotels with Suites 60
Holiday Apartments 52
Villas 3
Cabin Rentals 2
Cottages 2
Others 1

Use these Quick Filters to Find a Vacation Rental in Historic Southwest

Pro Tip: Old Mansions makes it easy to compare the best listings on Old Mansions homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Old Mansions homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Historic Southwest.

Weather in Historic Southwest

View the weather forecast for Historic Southwest before booking your Historic Southwest Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F